Table 2 Overview of the most frequently used mass spectrometer analyzers for metabolomics applications
Mass analyzer | Mass accuracy (ppm) | Resolving power (FWHM) (×103) | Mass range (m/z) (×103) |
|---|---|---|---|
Triple quadrupole (QqQ) | 5-500 | Up to 7.5 | 3 |
Ion trap (IT)/linear ion trap (LIT) | 50-500 | Up to ~10 | 4 |
Time of flight (TOF) | 1-2 | 10-60 | 5-40 |
Orbitrap | 1-5 | 140-240 | 4-6 |
Fourier transform ion cyclotron resonance (FT-ICR) | <1 | 750-1,000 | 4-10 |