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Chemical and Biological Technologies in Agriculture
Fig. 1 | Chemical and Biological Technologies in Agriculture

Fig. 1

From: Micromeria fruticosa and Foeniculum vulgare essential oils inhibit melanoma cell growth and migration by targeting MMP9 and NFkB signaling

Fig. 1

Fennel (Fe) and M. fruticosa (Thy) EOs inhibit melanoma cell growth. A Molecular structures of the major components found in EOs of Fe and Thy. B, C Murine B16F10 (B) and A431 cells (C) were treated with indicated concentrations of Fe-OE, Thy-OE given as monotherapy or in combination (Mix-EO). Viable cells were counted using Trypan blue exclusion after 24 h (n = 6/group). D Cell viability of B16F10 and A431 cells exposed to indicated concentrations of Mix-EO was determined using an MTT assay (n = 6/group). E Cell viability of murine peripheral blood mononuclear cells (PBMCs) after treatment with Mix–EO at indicated concentrations (n = 6/group). F, G Fold changes in BAX and anti-apoptosis-related BCL2 gene expression in Mix-EO-treated and control B16F10 (F) and A431 (G) cells. Expressions were compared to carrier controls. Data are expressed as mean ± SEM (unpaired Student's t test or one-way ANOVA *p < .05, **p < .01)

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