Skip to main content
Chemical and Biological Technologies in Agriculture
Fig. 3 | Chemical and Biological Technologies in Agriculture

Fig. 3

From: Micromeria fruticosa and Foeniculum vulgare essential oils inhibit melanoma cell growth and migration by targeting MMP9 and NFkB signaling

Fig. 3

Mix-EO treatment blocks melanoma growth in mice and suppresses systemic and tumor MMP9. A–D B16F10 cells were injected s.c. into the flank of C57/BL6 mice. Mice were treated with indicated dose combinations of EOs intraperitoneally (i.p.) daily starting from day 0. Twelve days after injection, microscopic tumor images were taken (A), and the tumor weight was measured (B; n = 6/group). C Collected tumors were analyzed for MMP9 expression by qPCR. Expression was compared to the expression in peripheral blood of non-tumor bearing mice (WT). D MMP9 plasma levels were determined on day 12 (n = 6/group). Data are expressed as mean ± SEM (unpaired Student's t test or one-way ANOVA *p < .05, **p < .01)

Back to article page