Micromeria fruticosa and Foeniculum vulgare essential oils inhibit melanoma cell growth and migration by targeting MMP9 and NFkB signaling

Chemical and Biological Technologies in Agriculture

Table 1 Phytochemical composition of fennel (Foeniculum vulgare) seed EO collected from the Nablus region, Palestine

Compound	R.T	RI	Content%
α-Pinene	9.79	931	0.06
Camphene	10.51	947	0.01
Sabinene	11.56	970	0.01
β-Pinene	11.75	974	0.08
Myrcene	12.35	987	0.08
Phellandrene	13.04	1003	0.10
p-Cymene	13.84	1022	0.05
Sylvestrene	14.11	1028	0.83
1,8-Cineole	14.13	1030	0.01
cis-Ocimene	14.40	1035	0.10
trans-Ocimene	14.83	1045	0.00
γ-Terpinene	15.31	1056	0.09
Fenchone	16.71	1089	3.93
Allo-Ocimene	18.00	1126	0.01
Camphor	18.87	1144	0.11
Terpinen-4-ol	20.23	1178	0.01
Methyl chavicol	20.92	1196	0.57
Octanol acetate	21.34	1207	0.01
endo-Fenchyl acetate	21.60	1215	0.03
exo-Fenchyl acetate	22.10	1229	0.16
cis-p-Anethole	22.89	1251	0.02
p-Anisaldehyde	23.02	1254	0.00
trans-Anethole	24.43	1294	93.69
Germacrene D	30.50	1480	0.01
Total			99.98
Monoterpene hydrocarbons			1.31
Oxygenated monoterpenes			98.66
Sesquiterpene hydrocarbons			0.01
Oxygenated sesquiterpenes			0.00