Skip to main content

Table 4 Antimicrobial activity and MIC of standard pure compounds as components of C. sativa

From: Identification and antimicrobial activity of most representative secondary metabolites from different plant species

Bacteria

THC

CBD

CBD/THC

ZoI (mm)a

MIC (mg L−1)

ZoI (mm)a

MIC (mg L−1)

ZoI (mm)a

MIC (mg L−1)

Gram+

 Bacillus cereus (A1I)

8.5 ± 1.2A

> 60

12.0 ± 1.0B

> 60

14.5 ± 1.4C

> 60

 Bacillus thuringiensis (B7I2)

9.5 ± 1.3A

> 60

13.0 ± 1.1B

> 60

14.5 ± 1.3C

> 60

 Bacillus amyloliquefaciens (A5TI)

8.0 ± 0.8A

> 60

11.0 ± 0.9B

> 60

15.0 ± 1.3C

> 60

Gram−

 Pseudomonas orientalis (A14-1II)

NI

NI

NI

 Stenotrophomonas maltophilia (B9TIII)

NI

NI

NI

  1. Assays were performed in triplicate and results are the mean of three values ± standard deviation
  2. NI no inhibition zone was observed, THC Δ9-tetrahydrocannabinol, CBD cannabidiol
  3. Different letters in superscript to numerical data indicate significant differences (p value < 0.05)
  4. aZoI: diameter of inhibition zone obtained after 24 h of incubation in agar well diffusion assays. ZoI < 10 mm: low
  5. antimicrobial activity; 11 < ZoI < 15 mm: middle antimicrobial activity; ZoI > 16 mm: high antimicrobial activity