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Chemical and Biological Technologies in Agriculture

Table 4 Anti-rotavirus activity of compounds 1–4

From: Antivirus isoindolinone alkaloids with rare oxocyclopenta[f]isoindole frameworks isolated from the stems of flue cured tobacco

No

CC50 (µg/mL)

EC50 (µg/mL)

TI (CC50/EC50)

1

172.2

13.2

13.0

2

247.2

14.4

17.2

3

206.4

13.2

15.6

4

218.5

11.8

18.5

Ribavirin

258.4

12.2

21.2

  1. CC50: mean (50%) value of cytotoxic concentration; EC50: mean (50%) value of effective concentration
  2. TI therapeutic index, CC50/EC50
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