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Table 6 Comparison between theoretical and experimental results at the optimum condition predicted by the model

From: Preparation of vitamin D3-loaded oil-in-water-in-oil double emulsions using psyllium gum: optimization using response surface methodology

Parameter

Theoretical

Experimental

Goal

Lower limit

Upper limit

Gum concentration (%)

1

1

In range

0

2

Surfactant concentration (%)

1.125

1.125

In range

0.25

2

Storage time (day)

25

25

In range

0

50

Z-average (nm)

433.42

432.27

Min.

214

1232

PDI

0.81

0.82

Min.

0.31

1.47

Zeta potential (mV)

− 36.66

− 36.45

Min.

− 63.2

− 11.3

Creaming index (%)

4.90

5.12

Min.

0

19.20

Interfacial tension (mN/m)

5.48

5.58

Min.

3.1

11.91

EE of primary emulsion (%)

83.33

83.12

Max.

51.31

93.26

EE of double emulsion (%)

93.26

93.28

Max.

65.52

98.81

  1. EE Encapsulation efficiency