Skip to main content

Table 4 Effects of DOP1 and DOP2 on carrageenan (Carr)-induced hind paw edema in rats

From: Polysaccharides from Dioscorea opposita Thunb.: isolation, structural characterization, and anti-inflammatory and anti-tumor effects against hepatocellular carcinoma

Group

Value of paw edema (ΔmL)

1 h

2 h

4 h

5 h

6 h

Carr-induced

0.225 ± 0.140

0.293 ± 0.110

0.280 ± 0.060

0.158 ± 0.030

0.095 ± 0.020

DOP1

     

 50 mg/kg

0.283 ± 0.029

0.417 ± 0.058

0.397 ± 0.075*

0.363 ± 0.085**

0.317 ± 0.076**

 200 mg/kg

0.150 ± 0.050

0.387 ± 0.030

0.360 ± 0.040*

0.327 ± 0.030**

0.267 ± 0.030**

 400 mg/kg

0.137 ± 0.100

0.173 ± 0.070

0.143 ± 0.010**

0.097 ± 0.030*

0.043 ± 0.010**

DOP2

     

 50 mg/kg

0.190 ± 0.042

0.195 ± 0.064

0.175 ± 0.064

0.115 ± 0.035

0.090 ± 0.014

 200 mg/kg

0.134 ± 0.056

0.158 ± 0.030

0.128 ± 0.030**

0.080 ± 0.030**

0.060 ± 0.020**

 400 mg/kg

0.053 ± 0.040

0.090 ± 0.040

0.063 ± 0.040**

0.037 ± 0.020**

0.017 ± 0.010**

  1. Data are represented as mean ± standard deviation (SD, n = 8). Significant difference analysis for each row, *P < 0.05, **P < 0.01