Group | Value of paw edema (ΔmL) | ||||
---|---|---|---|---|---|
1Â h | 2Â h | 4Â h | 5Â h | 6Â h | |
Carr-induced | 0.225 ± 0.140 | 0.293 ± 0.110 | 0.280 ± 0.060 | 0.158 ± 0.030 | 0.095 ± 0.020 |
DOP1 | Â | Â | Â | Â | Â |
 50 mg/kg | 0.283 ± 0.029 | 0.417 ± 0.058 | 0.397 ± 0.075* | 0.363 ± 0.085** | 0.317 ± 0.076** |
 200 mg/kg | 0.150 ± 0.050 | 0.387 ± 0.030 | 0.360 ± 0.040* | 0.327 ± 0.030** | 0.267 ± 0.030** |
 400 mg/kg | 0.137 ± 0.100 | 0.173 ± 0.070 | 0.143 ± 0.010** | 0.097 ± 0.030* | 0.043 ± 0.010** |
DOP2 | Â | Â | Â | Â | Â |
 50 mg/kg | 0.190 ± 0.042 | 0.195 ± 0.064 | 0.175 ± 0.064 | 0.115 ± 0.035 | 0.090 ± 0.014 |
 200 mg/kg | 0.134 ± 0.056 | 0.158 ± 0.030 | 0.128 ± 0.030** | 0.080 ± 0.030** | 0.060 ± 0.020** |
 400 mg/kg | 0.053 ± 0.040 | 0.090 ± 0.040 | 0.063 ± 0.040** | 0.037 ± 0.020** | 0.017 ± 0.010** |