Table 2 Experimental conditions for the Box–Behnken design and the corresponding responses measured
Exp. no. | X1 | X2 | X3 | X4 | Ball-to-material ratio (g/g) | Milling time (min) | Milling speed (rpm) | Extraction pH | Yield of calcium phytate (mg/g) |
|---|---|---|---|---|---|---|---|---|---|
1 | − 1 | − 1 | 0 | 0 | 10:1 | 10 | 300 | 5.5 | 20.0 |
2 | 1 | 0 | 0 | 1 | 26:1 | 30 | 300 | 7.0 | 64.8 |
3 | 1 | 0 | − 1 | 0 | 26:1 | 30 | 100 | 5.5 | 46.4 |
4 | − 1 | 0 | 0 | 1 | 10:1 | 30 | 300 | 7.0 | 34.6 |
5 | 0 | 0 | 0 | 0 | 18:1 | 30 | 300 | 5.5 | 92.2 |
6 | 0 | 0 | 0 | 0 | 18:1 | 30 | 300 | 5.5 | 93.0 |
7 | 0 | − 1 | 1 | 0 | 18:1 | 10 | 500 | 5.5 | 34.6 |
8 | 0 | 0 | 1 | 1 | 18:1 | 30 | 500 | 7.0 | 59.0 |
9 | 0 | 0 | − 1 | 1 | 18:1 | 30 | 100 | 7.0 | 32.4 |
10 | 0 | 1 | 1 | 0 | 18:1 | 50 | 500 | 5.5 | 68.0 |
11 | 0 | 1 | 0 | − 1 | 18:1 | 50 | 300 | 4.0 | 73.2 |
12 | 1 | 0 | 1 | 0 | 26:1 | 30 | 500 | 5.5 | 84.2 |
13 | 0 | 0 | 0 | 0 | 18:1 | 30 | 300 | 5.5 | 93.4 |
14 | 0 | − 1 | 0 | 1 | 18:1 | 10 | 300 | 7.0 | 26.4 |
15 | 0 | 0 | 0 | 0 | 18:1 | 30 | 300 | 5.5 | 94.0 |
16 | − 1 | 0 | 1 | 0 | 10:1 | 30 | 500 | 5.5 | 45.0 |
17 | 0 | − 1 | 0 | − 1 | 18:1 | 10 | 300 | 4.0 | 37.6 |
18 | 0 | 0 | 1 | − 1 | 18:1 | 30 | 500 | 4.0 | 83.4 |
19 | 0 | 1 | 0 | 1 | 18:1 | 50 | 300 | 7.0 | 52.0 |
20 | 1 | 1 | 0 | 0 | 26:1 | 50 | 300 | 5.5 | 74.2 |
21 | 1 | 0 | 0 | − 1 | 26:1 | 30 | 300 | 4.0 | 91.0 |
22 | − 1 | 1 | 0 | 0 | 10:1 | 50 | 300 | 5.5 | 39.6 |
23 | 0 | 1 | − 1 | 0 | 18:1 | 50 | 100 | 5.5 | 32.6 |
24 | 0 | 0 | 0 | 0 | 18:1 | 30 | 300 | 5.5 | 90.6 |
25 | − 1 | 0 | − 1 | 0 | 10:1 | 30 | 100 | 5.5 | 24.4 |
26 | 0 | 0 | − 1 | − 1 | 18:1 | 30 | 100 | 4.0 | 45.8 |
27 | − 1 | 0 | 0 | − 1 | 10:1 | 30 | 300 | 4.0 | 48.8 |
28 | 0 | − 1 | − 1 | 0 | 18:1 | 10 | 100 | 5.5 | 18.6 |
29 | 1 | − 1 | 0 | 0 | 26:1 | 10 | 300 | 5.5 | 38.2 |