Fig. 4

Venn diagram and pathway analysis of differential metabolites among different regions and in different fermentation stages of cigar tobacco leaf. D, J: Venn diagram showing the overlapping and accession-specific differential metabolites among the comparison groups. A–C, E–I: KEGG pathway enrichment based on the differential metabolites between the two comparison groups. A metabolic pathway is represented by each bubble. Abscissa and bubble size jointly represent the influence factors of this pathway. A larger impact factor and p values of the enrichment analysis are represented by a larger bubble size and the bubble colors, respectively. The darker colors represent higher enrichment levels